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Product Description
KAT Antibody | XW-8037 | ProSci
Host: Chicken
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: 301-511
Research Area: Neuroscience
Tested Application: WB
Application: Katanin p80 WD40-containing subunit B1 antibody can be used for the detection of Katanin p80 WD40-containing subunit B1 by Western Blot.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 72.3 kDa (calculated)
Validation: N/A
Isoform: N/A
Purification: Immunoaffinity Purified
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Condition: KAT antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: Katanin p80 WD40 repeat-containing subunit B1, p80 katanin, Katanin p80 subunit B1, KAT, Katanin p80 WD40containing subunit B1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: FUNCTION: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. This activity may promote rapid reorganization of cellular microtubule arrays, such as during disassembly of interphase microtubules at the G2-M transition. May also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body may allow their subsequent transport into neuronal processes by microtubule dependent motor proteins. This transport is required for axonal growth (By similarity) .
