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Product Description
NS Antibody | XW-7166 | ProSci
Host: Chicken
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: 1-280
Research Area: Homeostasis
Tested Application: WB
Application: E2IG3 antibody can be used for the detection of E2IG3 by Western blot, may also work for IHC and ICC.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 62 kDa (calculated)
Validation: N/A
Isoform: N/A
Purification: Antigen affinity-purified
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Condition: NS antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: E2IG3, NS, Guanine nucleotide-binding protein-like 3, E2-induced gene 3 protein, NNP47, E2IG3, C77032
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Nucleostemin; putative nucleotide binding protein, estradiol-induced; E2IG3. This protein may play a role in maintaining stem cell self-renewal. Depletion or overexpression of nucleostemin reduces cell proliferation in CNS stem cells and transformed cells. Mutation analysis indicated that excessive nucleostemin, particularly mutants lacking the GTP-regulatory domain, prevents cells from entering mitosis and causes apoptosis in a p53-dependent manner. The N-terminal basic domain mediates the interaction with p53 and is required for the cell death caused by overexpression.
