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Product Description
SGK Antibody | XW-7894 | ProSci
Host: Chicken
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: 211-431
Research Area: Neuroscience, Signal Transduction, Cancer
Tested Application: WB
Application: Serine/threonine-protein kinase Sgk1 antibody can be used for the detection of Serine/threonine-protein kinase Sgk1 by Western Blot.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 49 kDa (calculated)
Validation: N/A
Isoform: N/A
Purification: Immunoaffinity Purified
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Condition: SGK antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: SGK, SGK, Serine/threonineprotein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: FUNCTION: Protein kinase that plays an important role in cellular stress response. Activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. Sustained high levels and activity may contribute to conditions such as hypertension and diabetic nephropathy. Mediates cell survival signals, phosphorylates and negatively regulates pro-apoptotic FOXO3A. Phosphorylates NEDD4L, which leads to its inactivation and to the subsequent activation of various channels and transporters such as ENaC, Kv1.3, or EAAT1.
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