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Product Description
Ebselen | 10-023 | ProSci
BNR: Chemical
Predicted Molecular Weight: 274, 2
Physical State: Lyophilized
Storage Condition: Short Term Storage:+4C. Long Term Storage: -20C. Handling Advice: Protect from light. Use/Stability: Stable for at least 2 years after receipt when stored at -20C.
Alternate Name: 2-Phenyl-1, 2-benzisoselenazol-3- (2H) -one
Background: Glutathione peroxidase mimetic [1, 4]. Peroxynitrite scavenger [4]. Anti-inflammatory [1, 5-7] Antioxidant [2, 3, 5]. Protein kinase C (PKC), NADPH, lipoxygenase, COX, NOS, H+-ATPase and NADPH oxidase inhibitor [6-9]. Antifungal [9]. Review [10]. Potent IDO-1 inhibitor with Ki 94nM [11]. Inhibitor of HIV-1 capsid C-terminal domain dimerization. Shown to potentially inhibit the 33.8-kDa Main Protease (Mpro) /3C-like Protease of SARS-CoV-2, consequently inhibiting viral transcription and replication and possibly inhibiting spread of COVID-19
Disclaimer: This product is for research use only.
Purity: greater than or equal to 98% (HPLC)
Formula: C13H9NOSe
Source: N/A
Solubility: Soluble in DMSO (25mg/ml), DMF (25mg/ml) or water (2mg/ml) .
InChi Key: DYEFUKCXAQOFHX-UHFFFAOYSA-N
Smiles: O=C1N ([Se]C2=C1C=CC=C2) C1=CC=CC=C1
RTECS: N/A
Identity: Determined by 1H-NMR.
Merck Index: 3, 004166667
