Product Description
CD28 Antibody [PV-1] | 98-720 | ProSci
Host: Hamster
Reactivity: Mouse
Homology: N/A
Immunogen: C57BL/6N mouse T cell lymphoma EL4 cell line
Research Area: Immunology
Tested Application: IHC-P, IHC-Fr, ICC, Flow
Application: CD28 Antibody [PV-1] for use in flow cytometry, immunoprecipitation, costimulation, and stimulation assays.
Specificiy: CD28
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [PV-1]
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration: 0.5 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: Tp44, T44
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80 (B7-1) and CD86 (B7-2) on B cells and other antigen presenting cells and plays an important role in the interaction between T cells and B cells. CD28 is a costimulatory receptor involved in many, but not all, T-cell independent immune responses.