Product Description
CD79b Antibody [HM79-12] (Biotin) | 98-998 | ProSci
Host: Hamster
Reactivity: Mouse
Homology: N/A
Immunogen: CD79alpha/CD79beta heterodimers purified from mouse (BALB/c x NZB) F1 B cell lymphoma cells, WEHI231
Research Area: Immunology
Tested Application: Flow
Application: CD79b Antibody [HM79-12] for use in flow cytometry, western blotting, and immunoprecipitation assays.
Specificiy: CD79b
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [HM79-12]
Isotype: IgG
Conjugate: Biotin
Physical State: Liquid
Buffer: Supplied in PBS/NaN3
Concentration: 0.5 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: B29, Igbeta
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Murine CD79 is a disulfide-linked heterodimer composed of an alpha chain (CD79a) and a beta chain (CD79b) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation.