Product Description
TCR gamma delta Antibody [UC7-13D5] | 98-892 | ProSci
Host: Hamster
Reactivity: Mouse
Homology: N/A
Immunogen: Mouse T cell clone G8
Research Area: Immunology, Stem Cell
Tested Application: Flow, IP
Application: TCR gamma delta Antibody [UC7-13D5] for use in flow cytometry, immunoprecipitation, costimulaton, and depletion assays.
Specificiy: TCRgammadelta
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [UC7-13D5]
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration: 0.5 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: N/A
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The TCRgammadelta heterodimer of the CD3/T cell receptor complex is clonotypic and consists of Ig-like variable and constant domains. It is expressed during thymopoiesis and on the small subpopulation of gammadelta TCR-expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are gammadelta+ and have limited receptor diversity. The TCRgammadelta heterodimer recognizes peptide antigen bound to MHC antigens and subsequent signal transduction mediated by the invariant chains leads to T cell activation. The monoclonal antibody UC7-13D5 is specific for the gammadelta heterodimer and plate-bound UC7-13D5 activates gammadelta TCR-bearing cells. This antibody does not react with alphabeta TCR-expressing T cells.