Product Description
BATF3 Antibody | 7939 | ProSci
Host: Rabbit
Reactivity: Human
Homology: N/A
Immunogen: BATF3 antibody was raised against a 16 amino acid peptide near the amino terminus of human BATF3.
The immunogen is located within the first 50 amino acids of BATF3.
Research Area: Immunology, Stem Cell
Tested Application: E, WB, IHC-P, IF
Application: BATF3 body can be used for detection of BATF3 by Western blot at 0.5 μg/ml. Antibody can also be used for Immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Specificiy: BATF3 antibody is human, mouse and rat reactive. BATF3 antibody is predicted to have no cross-reactivity to other BATF family members.
Positive Control 1: Cat. No. 1210 - HEK293 Cell Lysate
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Predicted: 14 kDa
Observed: 17 kDa
Validation: N/A
Isoform: N/A
Purification: BATF3 antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: BATF3 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Condition: BATF3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Alternate Name: Basic leucine zipper transcriptional factor ATF-like 3, SNFT, JDP1, JUNDM1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: BATF3, also known as SNFT, belongs to the basic leucine zipper transcriptional family and functions as a transcriptional repressor when heterodimerizing with Jun (1) and can repress the transcription of IL-2 and MMP-1 (1, 2) . BATF3 is required for the development of CD8alpha+ classical dendritic cells (DCs) and the related CD103+ DCs that cross-present antigens to CD8 T cells (3, 4) .