Product Description
SLC29A4 Antibody | 8131 | ProSci
Host: Rabbit
Reactivity: Human
Homology: Predicted species reactivity based on immunogen sequence: Mouse: (94%)
Immunogen: SLC29A4 antibody was raised against an 18 amino acid peptide near the center of human SLC29A4.
The immunogen is located within amino acids 310 - 360 of SLC29A4.
Research Area: Cancer, Neuroscience
Tested Application: E, WB, IHC-P, IF
Application: SLC29A4 antibody can be used for detection of SLC29A4 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Specificiy: SLC29A4 antibody is human specific. SLC29A4 antibody is predicted to not cross-react with other SLC29 proteins.
Positive Control 1: Cat. No. 1220 - SK-N-SH Cell Lysate
Positive Control 2: Cat. No. 10-301 - Human Brain Tissue Slide
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Predicted: 58 kDa
Observed: 58 kDa
Validation: N/A
Isoform: N/A
Purification: SLC29A4 antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: SLC29A4 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Condition: SLC29A4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Alternate Name: Solute carrier family 29 member 4, Equilibrative nucleoside transporter 4, ENT4, PMAT
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: SLC29A4 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1, 2) . SLC29A4 is a transmembrane protein that catalyzes the reuptake of monoamines into presynaptic neurons, thus determining the intensity and duration of monoamine neural signaling (1, 3) . SLC29A4 has been shown to transport several compounds, including serotonin, dopamine, and the neurotoxin 1-methyl-4-phenylpyridinium (3) .