Euro
USD
British Pound
NULL
Product Description
ITGAE Antibody | 23-983 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-200 of human ITGAE (NP_002199.3) .
Research Area: Cell Cycle, Immunology, Signal Transduction, Stem Cell
Tested Application: WB, IHC
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: 293T
Positive Control 2: SW620
Positive Control 3: HeLa
Positive Control 4: Mouse lung
Positive Control 5: Mouse thymus
Positive Control 6: N/A
Molecular Weight: Observed: 110kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: Integrin alpha-E, HML-1 antigen, Integrin alpha-IEL, Mucosal lymphocyte 1 antigen, CD103, Integrin alpha-E light chain, Integrin alpha-E heavy chain, ITGAE
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL) , and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.
