Product Description
PDCD1 / PD-1 Antibody | 33-741 | ProSci
Host: Rabbit
Reactivity: Human
Homology: N/A
Immunogen: A full-length human protein was used as the immunogen for the PD1 antibody.
Research Area: Immunology, Cancer, Cell Cycle
Tested Application: IHC-P, IF, Flow
Application: Immunohistochemistry (FFPE) : 1-2 ug/ml for 30 min at RT
Immunofluorescence: 1-2 ug/ml
Flow Cytometry: 0.5-1ug/10e6 cells in 0.1ml
Titering of the PD1 antibody may be required for optimal performance.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein A affinity chromatography
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
Alternate Name: PD-1 Antibody: PD1, PD-1, CD279, SLEB2, hPD-1, hPD-l, hSLE1, PD1, Programmed cell death protein 1, Protein PD-1, PDCD1, PDCD-1
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: PDCD1 (Programmed cell death-1 protein) , also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.