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Product Description
RASGRP3 Antibody | 23-186 | ProSci
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 540-689 of human RASGRP3 (NP_056191.1) .
Research Area: Immunology, Signal Transduction
Tested Application: WB, IF
Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: BT-474
Positive Control 2: A-549
Positive Control 3: Mouse heart
Positive Control 4: Mouse lung
Positive Control 5: Mouse thymus
Positive Control 6: N/A
Molecular Weight: Observed: 78kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: GRP3, ras guanyl-releasing protein 3, CalDAG-GEFIII, RAS guanyl releasing protein 3 (calcium and DAG-regulated) , calcium and DAG-regulated guanine nucleotide exchange factor III, calcium- and diacylglycerol-regulated guanine nucleotide exchange factor III, guanine nucleotide exchange factor for Rap1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers.
