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Product Description
IL-15 mutant Recombinant Protein | 90-504 | ProSci
Tested Application: N/A
Application: This recombinant proteins is for research use only.
Tpredicted Molecular Weight: N/A
Physical State: Lyophilized
Buffer: Lyophilized from 0.2um-filtered solution in PBS. Reconstitute in 50 μl sterile water. Add 1X PBS to the desired protein concentration.
Storage Condition: Stable for at least 1 year after receipt when stored at -20˚C. Working aliquots are stable for up to 3 months when stored at -20˚C.
Alternate Name: Interleukin-15
Background: N/A
Shipping: N/A
Disclaimer: Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Source: CHO cells
Species: Human
By Source: CHO Cells
By Species: Human
Fusion Tag: Fc Tag
Sequence: The extracellular domain of human IL-15 (aa 49-162) including mutations at Q149D and Q156D is fused to the N-terminus of the Fc region of human IgG1.
Bological Activity: This mutant IL-15/Fc fusion protein specifically binds to the IL-15R, competitively inhibits IL-15-triggered cell proliferation, promotes transplant tolerance, does not activate the STAT-signaling pathway, and exerts a prolonged circulating half-life caused by the modified Fc domain.
Purity: >98% (SDS-PAGE).
Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
