Euro
USD
British Pound
NULL
![CD11a Antibody [CRIS-3]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/575021/811187/porsci_lo__79508.1648973713__60289.1649091789.png?c=2 "CD11a Antibody [CRIS-3]")
![CD11a Antibody [CRIS-3]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/575021/811187/porsci_lo__79508.1648973713__60289.1649091789.png?c=2 "CD11a Antibody [CRIS-3]")
Product Description
CD11a Antibody [CRIS-3] | 33-156 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Stimulated human leukocytes were used as the immunogen for this CD11b antibody.
Research Area: Immunology, Signal Transduction
Tested Application: WB, Flow, IF, Func
Application: Functional Testing: order BSA/azide-free format
Flow Cytometry: 0.5-1 ug/million cells
IF: 0.5-1 ug/ml
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein G affinity chromatography
Clonality: Monoclonal
Clone: CRIS-3
Isotype: IgG2b, kappa
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
Alternate Name: Integrin alpha-L, CD11 antigen-like family member A, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, Leukocyte function-associated molecule 1 alpha chain, CD11a, ITGAL, CD11A
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: This antibody recognizes a protein of 180kDa, identified as CD11a. CD11a complexes with the beta 2 subunit of the integrin family, CD18, to form the cell surface heterodimer called LFA-1 or CD11a/CD18. LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54) , ICAM-2 (CD102) , ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses.
![CD11a Antibody [CRIS-3]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/575021/811187/porsci_lo__79508.1648973713__60289.1649091789.png?c=2 "CD11a Antibody [CRIS-3]")
