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![CD14 Antibody [61D3] (PerCP-Cy5.5)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/555604/764564/porsci_lo__79508.1648973713__18731.1649086655.png?c=2 "CD14 Antibody [61D3] (PerCP-Cy5.5)")
![CD14 Antibody [61D3] (PerCP-Cy5.5)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/555604/764564/porsci_lo__79508.1648973713__18731.1649086655.png?c=2 "CD14 Antibody [61D3] (PerCP-Cy5.5)")
Product Description
CD14 Antibody [61D3] (PerCP-Cy5.5) | 76-391 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: N/A
Research Area: Innate Immunity
Tested Application: Flow
Application: N/A
Specificiy: The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality: Monoclonal
Clone: 61D3
Isotype: Mouse IgG1, kappa
Conjugate: PerCP-Cy5.5
Physical State: liquid
Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration: batch dependent
Storage Condition: The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze.
Alternate Name: CD14, CD14
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB.
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