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![CD22 Antibody [MYG13]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/575329/811896/porsci_lo__79508.1648973713__91206.1649091893.png?c=2 "CD22 Antibody [MYG13]")
![CD22 Antibody [MYG13]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/575329/811896/porsci_lo__79508.1648973713__91206.1649091893.png?c=2 "CD22 Antibody [MYG13]")
Product Description
CD22 Antibody [MYG13] | 33-492 | ProSci
Host: Mouse
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Human Raji cells were used as the immunogen for the CD22 antibody.
Research Area: Cancer, Stem Cell, Immunology, Antibody Pairs
Tested Application: WB, Func, Flow, IF
Application: Functional Activity (Order SAF formulation)
Flow Cytometry: 0.5-1 ug/million cells in 0.1ml
Immunofluorescence: 0.5-1 ug/ml
Optimal dilution of the CD22 antibody should be determined by the researcher.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein G affinity chromatography
Clonality: Monoclonal
Clone: MYG13
Isotype: IgG1, kappa
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
Alternate Name: SIGLEC2, SIGLEC-2
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: Recognizes a protein of 130-140kDa, identified as CD22 (also known as BL-CAM) . CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.
![CD22 Antibody [MYG13]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/575329/811896/porsci_lo__79508.1648973713__91206.1649091893.png?c=2 "CD22 Antibody [MYG13]")
