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![CD28 Antibody [CD28.2]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/555932/764936/porsci_lo__79508.1648973713__14352.1649086700.png?c=2 "CD28 Antibody [CD28.2]")
![CD28 Antibody [CD28.2]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/555932/764936/porsci_lo__79508.1648973713__14352.1649086700.png?c=2 "CD28 Antibody [CD28.2]")
Product Description
CD28 Antibody [CD28.2] | 76-726 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: N/A
Research Area: Immunology, Functional Assays
Tested Application: Flow, Func, IHC, IP
Application: N/A
Specificiy: The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Clonality: Monoclonal
Clone: CD28.2
Isotype: Mouse IgG1, kappa
Conjugate: Unconjugated
Physical State: liquid
Buffer: Phosphate-buffered aqueous solution, ph7.2.
Concentration: batch dependent
Storage Condition: The product should be stored undiluted at 4˚C . Do not freeze.
Alternate Name: Tp44, CD28
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes. CD28 is a ligand for B7-1 (CD80) and B7-2 (CD86) , a co-stimulator of T lymphocytes, and enhances the interaction between T and B lymphocytes. It has been reported that the T lymphocytes stimulation to produce IL-2 depends on the monoclonal antibody involved, which suggests that the CD28 molecule presents some subregions with distinct functions. The CD28.2 antibody induces Ca2+ influx in Jurkat T lymphocytes. Other studies have shown that CD28 is involved in the signal transduction.
![CD28 Antibody [CD28.2]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/555932/764936/porsci_lo__79508.1648973713__14352.1649086700.png?c=2 "CD28 Antibody [CD28.2]")
![CD28 Antibody [CD28.2]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/555931/764935/porsci_lo__79508.1648973713__72996.1649086700.png?c=2 "CD28 Antibody [CD28.2]")
![CD28 Antibody [CD28.2]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/555933/764937/porsci_lo__79508.1648973713__20750.1649086700.png?c=2 "CD28 Antibody [CD28.2]")
![CD28 Antibody [CD28.2] (FITC)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/555935/764940/porsci_lo__79508.1648973713__40256.1649086700.png?c=2 "CD28 Antibody [CD28.2] (FITC)")
![CD28 Antibody [CD28.2] (APC)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/555942/764950/porsci_lo__79508.1648973713__90478.1649086701.png?c=2 "CD28 Antibody [CD28.2] (APC)")
![CD28 Antibody [CD28.2] (PE)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/555936/764942/porsci_lo__79508.1648973713__48429.1649086701.png?c=2 "CD28 Antibody [CD28.2] (PE)")