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![IL-10 Antibody [3C12C12]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/553091/760865/porsci_lo__79508.1648973713__14627.1649086142.png?c=2 "IL-10 Antibody [3C12C12]")
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Product Description
IL-10 Antibody [3C12C12] | 32-227 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Ni-NTA purified recombinant human IL-10 expressed in E. Coli strain BL21 (DE3) .
Research Area: Immunology, Innate Immunity
Tested Application: E, WB
Application: Western Blot:1:500 - 1, 000
ELISA:Determining optimal working dilutions by titration test.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Antibody is purified by protein A affinity chromatography.
Clonality: Monoclonal
Clone: 3C12C12
Isotype: IgG1.kappa
Conjugate: Unconjugated
Physical State: N/A
Buffer: Purified antibody in PBS containing 0.03% sodium azide.
Concentration: N/A
Storage Condition: to IL-10 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: Cytokine synthesis inhibitory factor, IL-10, CSIF, TGIF, GVHDS, IL10A
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Interleukine 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down- regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
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