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![Neurofilament NF-M Antibody [3H11]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/553221/761133/porsci_lo__79508.1648973713__07424.1649086177.png?c=2 "Neurofilament NF-M Antibody [3H11]")
![Neurofilament NF-M Antibody [3H11]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/553221/761133/porsci_lo__79508.1648973713__07424.1649086177.png?c=2 "Neurofilament NF-M Antibody [3H11]")
Product Description
Neurofilament NF-M Antibody [3H11] | 50-257 | ProSci
Host: Mouse
Reactivity: Human, Mouse, Rat, Chicken
Homology: N/A
Immunogen: Recombinant fusion protein containing the extreme C-terminus of rat NF-M expressed in and purified from E. coli.
Research Area: Neuroscience
Tested Application: WB, IHC
Application: N/A
Specificiy: Specific for the ~145k Neurofilament M protein.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 145
Validation: N/A
Isoform: N/A
Purification: Total IgG fraction
Clonality: Monoclonal
Clone: 3H11
Isotype: IgG1
Conjugate: Unconjugated
Physical State: Liquid
Buffer: N/A
Concentration: N/A
Storage Condition: Neurofilament NF-M antibody can be stored at -20˚C and is stable at -20˚C for at least 1 year.
Alternate Name: N/A
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease.
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