Product Description
Thymidylate Synthase Antibody [2D8.D11] | 47-129 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Recombinant human thymidylate synthase produced in E. coli.
Research Area: Cancer
Tested Application: N/A
Application: N/A
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: 2D8.D11
Isotype: IgG1
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS
Concentration: N/A
Storage Condition: This antibody is stable for at least one (1) year at -20˚C. Avoid multiple freeze- thaw cycles.
Alternate Name: RAD51A, RECA, DNA repair protein RAD51 homolog 1, RAD51 homolog A, HsRAD51, BRCC5, MRMV2, HRAD51, HsRad51, HsT16930
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Thymidylate synthase (TS) is anintracellular enzyme critical for de novosynthesis of DNA. In cancer, expression of TS is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU) . Resistance or lack of response to 5-FU is attributed to the elevation of TS activity. Overexpression of TS has been demonstrated in many types of tumors including breast, colon, gastric and melanoma and is usually predictive of shortened survival time.