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Product Description
Adipophilin Antibody [ADFP/1493] | 33-587 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: A human partial recombinant protein was used as the immunogen for this PLIN2 antibody.
Research Area: Cancer, Obesity, Signal Transduction
Tested Application: IHC-P, IF, E
Application: ELISA: order formulation without BSA for coating
IHC (FFPE) : 1-2 ug/ml
IF: 1-2 ug/ml
Titering of the PLIN2 antibody may be required for optimal performance.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein G affinity chromatography
Clonality: Monoclonal
Clone: ADFP/1493
Isotype: IgG2b, kappa
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
Alternate Name: Perilipin-2, Adipophilin, Adipose differentiation-related protein, ADRP, PLIN2, ADFP
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: Adipophilin, also called Perilipin 2, ADRP (Adipose differentiation related protein) , and PLIN2, belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material and maybe involved in development and maintenance of adipose tissue. It is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.
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