Euro
USD
British Pound
NULL
![Bcl6 Antibody [BCL6/1527]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/575632/812637/porsci_lo__79508.1648973713__15758.1649091988.png?c=2 "Bcl6 Antibody [BCL6/1527]")
![Bcl6 Antibody [BCL6/1527]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/575632/812637/porsci_lo__79508.1648973713__15758.1649091988.png?c=2 "Bcl6 Antibody [BCL6/1527]")
Product Description
Bcl6 Antibody [BCL6/1527] | 33-840 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Amino acids 256-389 were used as the immunogen for the Bcl6 antibody.
Research Area: Cancer, Cell Cycle
Tested Application: WB, Flow, IF, IHC-P
Application: Flow Cytometry: 0.5-1 ug/million cells in 0.1ml
Immunofluorescence: 1-2 ug/ml
Immunohistochemistry (FFPE) : 0.125-0.25 ug/ml
Prediluted IHC only format: incubate for 30 min at RT (1)
Optimal dilution of the Bcl6 antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required) , drip mAb solution onto the tissue section and incubate at RT for 30 min.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein G affinity chromatography
Clonality: Monoclonal
Clone: BCL6/1527
Isotype: IgG1, kappa
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
Alternate Name: BCL6 Antibody: BCL5, LAZ3, BCL6A, ZNF51, ZBTB27, BCL5, B-cell lymphoma 6 protein, B-cell lymphoma 5 protein, BCL-6
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: Antibody to Bcl-6 is helpful in a number of diagnostic settings: First, in the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show Bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. Second, Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL) , where CD10, Bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. Third, Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) . The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large (L&H) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
![Bcl6 Antibody [BCL6/1527]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/575632/812637/porsci_lo__79508.1648973713__15758.1649091988.png?c=2 "Bcl6 Antibody [BCL6/1527]")
![Bcl6 Antibody [BCL6/1526]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/575605/812574/porsci_lo__79508.1648973713__06454.1649091980.png?c=2 "Bcl6 Antibody [BCL6/1526]")
![Bcl6 Antibody [BCL6/1475]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/575631/812634/porsci_lo__79508.1648973713__55111.1649091987.png?c=2 "Bcl6 Antibody [BCL6/1475]")
