Product Description
CD11a Antibody [38] (Biotin) | 99-342 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Fibronectin purified monocytes
Research Area: Immunology, Signal Transduction
Tested Application: Flow
Application: CD11a Antibody [38] for use in flow cytometry, immunohistochemistry, ELISA, and immunoprecipitation assays.
Specificiy: CD11a
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [38]
Isotype: IgG2a
Conjugate: Biotin
Physical State: Liquid
Buffer: Supplied in PBS/NaN3
Concentration: Lot specific
Storage Condition: Store vial at 2-8˚C
Alternate Name: LFA-1alpha, integrin alphaL, ITGAL
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD11a, also known as leukocyte function-associated antigen-1 (LFA-1alpha) , represents the 180 kDa integrin alphaL subunit which combines with the CD18 beta2 integrin subunit to form the alphaLbeta2 integrin heterodimer. It is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T cells. CD11a mediates adhesion of lymphocytes to vascular endothelium and is involved in costimulation.