Product Description
CD14 Antibody [61D3] (PE-Cy5) | 99-484 | ProSci
Host: Mouse
Reactivity: Human, Cynomolgus, Dog, Hooded Seal
Homology: N/A
Immunogen: Human peripheral monocytes
Research Area: Immunology, Signal Transduction
Tested Application: IHC-Fr, Flow, Blocking, Adhesion, Costimulation
Application: CD14 Antibody [61D3] for use in flow cytometry assays.
Specificiy: CD14
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [61D3]
Isotype: IgG1
Conjugate: PE-Cy5
Physical State: Liquid
Buffer: Supplied in PBS/NaN3 and a stabilizing agent
Concentration: Lot specific
Storage Condition: Store vial at 2-8˚C
Alternate Name: LPS-R, LPS receptor, gp55
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD14 is a 55 kDa glycosphosphatidylinositol (GPI) -anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells, and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.