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![CD162 Antibody [PSGL1/1601]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/575429/812127/porsci_lo__79508.1648973713__31458.1649091922.png?c=2 "CD162 Antibody [PSGL1/1601]")
![CD162 Antibody [PSGL1/1601]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/575429/812127/porsci_lo__79508.1648973713__31458.1649091922.png?c=2 "CD162 Antibody [PSGL1/1601]")
Product Description
CD162 Antibody [PSGL1/1601] | 33-602 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Recombinant human PSGL-1 protein was used as the immunogen for the PSGL-1 antibody.
Research Area: Immunology
Tested Application: Flow, IF, IHC-P
Application: Flow Cytometry: 0.5-1 ug/million cells in 0.1ml
Immunofluorescence: 0.5-1 ug/ml
Immunohistochemistry (FFPE) : 1-2 ug/ml for 30 min at RT
Optimal dilution of the PSGL-1 antibody should be determined by the researcher.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein G affinity
Clonality: Monoclonal
Clone: PSGL1/1601
Isotype: IgG1
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
Alternate Name: P-selectin glycoprotein ligand 1, PSGL-1, Selectin P ligand, CD162, SELPLG
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: P selectin glycoprotein ligand 1 (PSGL-1) , also called CD162 glycoprotein, functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.
![CD162 Antibody [PSGL1/1601]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/575429/812127/porsci_lo__79508.1648973713__31458.1649091922.png?c=2 "CD162 Antibody [PSGL1/1601]")
