Product Description
CD25 Antibody [BC96] (PE) | 99-503 | ProSci
Host: Mouse
Reactivity: Human, Rhesus, Cynomolgus
Homology: N/A
Immunogen: N/A
Research Area: Immunology
Tested Application: WB, IHC-P, IHC-Fr, Flow
Application: CD25 Antibody [BC96] for use in flow cytometry assays.
Specificiy: CD25
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [BC96]
Isotype: IgG1
Conjugate: PE
Physical State: Liquid
Buffer: Supplied in PBS/NaN3 and a stabilizing agent
Concentration: Lot specific
Storage Condition: Store vial at 2-8˚C
Alternate Name: IL-2Ralpha, Tac antigen
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The BC96 monoclonal antibody reacts with human CD25, the 55 kDa interleukin-2 receptor alpha chain (IL-2Ralpha) . CD25 is expressed by early progenitors of T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor. CD25 plays a role in lymphocyte differentiating and activation/proliferation. CD25 is expressed on activated B cells, monocytes/macrophages, and T cells.