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![CD44 Antibody [F10-44-2]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/576890/814872/porsci_lo__79508.1648973713__53121.1649092283.png?c=2 "CD44 Antibody [F10-44-2]")
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Product Description
CD44 Antibody [F10-44-2] | 99-380 | ProSci
Host: Mouse
Reactivity: Human, Ma's Night Monkey
Homology: N/A
Immunogen: Purified human T cells
Research Area: Signal Transduction, Signal Transduction
Tested Application: IHC-Fr, Flow
Application: CD44 Antibody [F10-44-2] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, CMCD, cytotoxicity, depletion, adhesion, activation, purification, and blocking assays.
Specificiy: CD44
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [F10-44-2]
Isotype: IgG2a
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in PBS
Concentration: 0.5 mg/mL
Storage Condition: Store vial at -20˚C
Alternate Name: Pgp-1, H-CAM, ECMR-III, HUTCH-1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD44, also known as phagocytic glycoprotein-1 (Pgp-1) , exists as a large number of different isoforms resulting from alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type I transmembrane protein. Other variable isoforms containing glycosaminoglycans have molecular weights ranging from 110 to 250 kDa and are widely expressed on hematopoietic and non-hematopoietic cells. CD44 contributes to the adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix. It also plays a functional role in cell migration, lymphocyte homing, and adhesion during hematopoiesis and lymphocyte activation.
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