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![CD54 Antibody [15.2] (FITC)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/577079/815121/porsci_lo__79508.1648973713__47968.1649092315.png?c=2 "CD54 Antibody [15.2] (FITC)")
![CD54 Antibody [15.2] (FITC)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/577079/815121/porsci_lo__79508.1648973713__47968.1649092315.png?c=2 "CD54 Antibody [15.2] (FITC)")
Product Description
CD54 Antibody [15.2] (FITC) | 99-389 | ProSci
Host: Mouse
Reactivity: Human, Pig
Homology: N/A
Immunogen: Rheumatoid synovial cells and human monocytes
Research Area: Immunology, Signal Transduction
Tested Application: Flow
Application: CD54 Antibody [15.2] for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
Specificiy: CD54
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [15.2]
Isotype: IgG1
Conjugate: FITC
Physical State: Liquid
Buffer: Supplied in PBS/NaN3
Concentration: Lot specific
Storage Condition: Store vial at 2-8˚C
Alternate Name: ICAM-1, intracellular adhesion molecule-1, Ly-47
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD54, also known as intercellular cell adhesion molecule-1 (ICAM-1) , is a 90 kDa type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It exhibits a wide tissue distribution being expressed on both hematopoietic and non-hematopoietic cells. ICAM-1 expression on leukocytes is low but is rapidly upregulated upon activation. Expression on endothelium and other non-hematopoietic cells is strongly upregulated by inflammatory mediators. The ligands of CD54 are CD11a/LFA-1alpha and CD11b/Mac-1alpha. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels particularly in areas of inflammation. CD54 on antigen-presenting cells (APC) contributes to antigen-specific T cell activation presumably by enhancing interactions between T cells and APC.
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![CD54 Antibody [15.2] (APC)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/577082/815125/porsci_lo__79508.1648973713__93753.1649092315.png?c=2 "CD54 Antibody [15.2] (APC)")
![CD54 Antibody [15.2] (Biotin)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/577080/815122/porsci_lo__79508.1648973713__98903.1649092315.png?c=2 "CD54 Antibody [15.2] (Biotin)")
![CD54 Antibody [15.2] (PE)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/577081/815123/porsci_lo__79508.1648973713__14476.1649092315.png?c=2 "CD54 Antibody [15.2] (PE)")
![CD54 Antibody [15.2] (FITC)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/555645/764605/porsci_lo__79508.1648973713__17400.1649086661.png?c=2 "CD54 Antibody [15.2] (FITC)")