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![Cytokeratin 18 Antibody [SB38b] (FITC)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/576362/814110/porsci_lo__79508.1648973713__57115.1649092182.png?c=2 "Cytokeratin 18 Antibody [SB38b] (FITC)")
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Product Description
Cytokeratin 18 Antibody [SB38b] (FITC) | 99-629 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Recombinant N-terminal cytokeratin 18
Research Area: Signal Transduction
Tested Application: Flow, IP, Activity
Application: Cytokeratin 18 Antibody [SB38b] for use in flow cytometry, immunocytochemistry, and western blotting assays.
Specificiy: Cytokeratin 18
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [SB38b]
Isotype: IgG2b
Conjugate: FITC
Physical State: Liquid
Buffer: Supplied in PBS/NaN3
Concentration: 0.5 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: CK 18, keratin 18
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8) . The two keratin types share only 30% sequence homology. Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 18 is a type I intermediate filament protein that exists as a heterotetramer composed of two type I and two type II keratins. Cytokeratin 18 is expressed in all simple type epithelia and basal cells of many squamous and non-epidermal epithelia and is often co-expressed with cytokeratin 8. Tissues from the gastrointestinal tract, respiratory tract, and urogenital tract as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
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