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![DC-SIGN Antibody [C209/1781]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/575601/812564/porsci_lo__79508.1648973713__92341.1649091979.png?c=2 "DC-SIGN Antibody [C209/1781]")
![DC-SIGN Antibody [C209/1781]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/575601/812564/porsci_lo__79508.1648973713__92341.1649091979.png?c=2 "DC-SIGN Antibody [C209/1781]")
Product Description
DC-SIGN Antibody [C209/1781] | 33-797 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: A human partial recombinant protein was used as the immunogen for the DC-SIGN antibody.
Research Area: Infectious Disease
Tested Application: WB, Flow, IF, IHC-P
Application: IF: 1-2 ug/ml
Flow Cytometry: 0.5-1 ug/million cells in 0.1ml
IHC (FFPE) : 0.5-1 ug/ml for 30 min at RT
Titering of the DC-SIGN antibody may be required for optimal performance.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein G affinity chromatography
Clonality: Monoclonal
Clone: C209/1781
Isotype: IgG2b, kappa
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
Alternate Name: DC-SIGN Antibody: CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1, CD209 antigen, C-type lectin domain family 4 member L
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: DC-SIGN / CD209 is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.
![DC-SIGN Antibody [C209/1781]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/575601/812564/porsci_lo__79508.1648973713__92341.1649091979.png?c=2 "DC-SIGN Antibody [C209/1781]")
