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Product Description
Foxp3 Antibody [3G3] (APC) | 77-151 | ProSci
Host: Mouse
Reactivity: Mouse
Homology: N/A
Immunogen: N/A
Research Area: Immunology
Tested Application: Flow, WB
Application: N/A
Specificiy: The 3G3 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX) , a member of the forkhead family of transcription factors.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality: Monoclonal
Clone: 3G3
Isotype: Mouse IgG1, kappa
Conjugate: APC
Physical State: liquid
Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration: batch dependent
Storage Condition: The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze.
Alternate Name: sf, JM2, scurfin, Foxp3
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The 3G3 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX) , a member of the forkhead family of transcription factors. Foxp3 is expressed by the Treg lymphocytes, whose development and function are influenced by the forkhead protein. Ectopic expression of Foxp3 in T lymphocytes inhibits their activity and cytokine expression.Mutations of Foxp3 result in the “scurfy” mice phenotype.
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