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![Gamma Catenin Antibody [15F11]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/575415/812095/porsci_lo__79508.1648973713__47923.1649091918.png?c=2 "Gamma Catenin Antibody [15F11]")
![Gamma Catenin Antibody [15F11]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/575415/812095/porsci_lo__79508.1648973713__47923.1649091918.png?c=2 "Gamma Catenin Antibody [15F11]")
Product Description
Gamma Catenin Antibody [15F11] | 33-586 | ProSci
Host: Mouse
Reactivity: Human, Mouse, Rat, Cat, Dog, Chicken, Bovine
Homology: N/A
Immunogen: Recombinant full length chicken gamma Catenin was used as the immunogen for the Plakoglobin antibody.
Research Area: Signal Transduction
Tested Application: IF, WB, IP
Application: Immunofluorescence: 1-2 ug/ml
WB: 0.5-1 ug/ml
Immunoprecipitation: suitable
The stated application concentrations are suggested starting amounts. Titration of the Plakoglobin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein G affinity chromatography
Clonality: Monoclonal
Clone: 15F11
Isotype: IgG1, kappa
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
Alternate Name: Junction plakoglobin, Catenin gamma, Desmoplakin III, Desmoplakin-3, JUP, CTNNG, DP3
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: Plakoglobin, or gamma Catenin, is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of Plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity) . [UniProt]
![Gamma Catenin Antibody [15F11]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/575415/812095/porsci_lo__79508.1648973713__47923.1649091918.png?c=2 "Gamma Catenin Antibody [15F11]")
![Gamma Catenin Antibody [11E4.]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/575414/812093/porsci_lo__79508.1648973713__60275.1649091918.png?c=2 "Gamma Catenin Antibody [11E4.]")
