Product Description
Glycophorin A Antibody [CMRF14] (PE) | 99-612 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: N/A
Research Area: Homeostasis
Tested Application: IHC-Fr, Flow
Application: Glycophorin A Antibody [CMRF14] for use in flow cytometry assays.
Specificiy: Glycophorin A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [CMRF14]
Isotype: IgG2b
Conjugate: PE
Physical State: Liquid
Buffer: Supplied in PBS/NaN3 and a stabilizing agent
Concentration: Lot specific
Storage Condition: Store vial at 2-8˚C
Alternate Name: CD235a, GYPA, GPA
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Glycophorin A (CD235a) is a 36 kDa sialoglycoprotein that is the most predominant sialoglycoprotein of the erythroid lineage. Glycophorin A is the major contributor to the net negative surface charge of the mature red blood cell (RBC) membrane thereby minimizing cell to cell interactions in circulation. The monoclonal antibody CMRF14 binds to glutaraldehyde fixed or neuraminidase treated erythrocytes but not to papain, trypsin, or pronase treated erythrocytes.