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![Ly-49I Antibody [YLI-90] (FITC)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/576634/814517/porsci_lo__79508.1648973713__18669.1649092236.png?c=2 "Ly-49I Antibody [YLI-90] (FITC)")
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Product Description
Ly-49I Antibody [YLI-90] (FITC) | 98-939 | ProSci
Host: Mouse
Reactivity: Mouse
Homology: N/A
Immunogen: CHO-K1 cells transfected with B6 allele of Ly49I gene
Research Area: Immunology
Tested Application: Flow
Application: Ly-49I Antibody [YLI-90] for use in flow cytometry assays.
Specificiy: Ly-49I
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [YLI-90]
Isotype: IgG1
Conjugate: FITC
Physical State: Liquid
Buffer: Supplied in PBS/NaN3
Concentration: 0.5 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: Ly-49
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The monoclonal antibody YLI-90 reacts with the B6 allele of Ly49I, a member of the lectin-like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells. The YLI-90 antibody stains ~45% of NK1.1+CD3- splenocytes from C57BL/6 mice.
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