Product Description
MHC Class I Antibody [F21-2] (Biotin) | 99-276 | ProSci
Host: Mouse
Reactivity: Chicken, Turkey
Homology: N/A
Immunogen: N/A
Research Area: Immunology
Tested Application: Flow
Application: MHC Class I Antibody [F21-2] for use in flow cytometry, immunohistochemistry, electron microscopy, western blotting, and immunoprecipitation assays.
Specificiy: MHC Class I
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [F21-2]
Isotype: IgG1
Conjugate: Biotin
Physical State: Liquid
Buffer: Supplied in PBS/NaN3
Concentration: 0.5 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: B-F
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Like their mammalian counterparts, avian MHC Class I molecules, also known as B-F antigens, consist of a highly polymorphic alpha-chain noncovalently bound to the invariant beta2-microglobulin subunit. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. The monoclonal antibody F21-2 also reacts with turkey MHC Class I.