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![Neurofilament NF-H Antibody [NAP4]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/553217/761125/porsci_lo__79508.1648973713__46800.1649086176.png?c=2 "Neurofilament NF-H Antibody [NAP4]")
![Neurofilament NF-H Antibody [NAP4]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/553217/761125/porsci_lo__79508.1648973713__46800.1649086176.png?c=2 "Neurofilament NF-H Antibody [NAP4]")
Product Description
Neurofilament NF-H Antibody [NAP4] | 50-253 | ProSci
Host: Mouse
Reactivity: Chicken, Mammal
Homology: N/A
Immunogen: Purified bovine NF-H.
Research Area: Neuroscience
Tested Application: WB, IHC
Application: N/A
Specificiy: Specific for the ~200k Neurofilament H protein. It recognizes phosphorylated NF-H KSP (lysine-serine-proline) type sequences. In some species there is some cross-reactivity with the related phosphorylated KSP sequences found in the related neurofilament subunit NF-M. It recognizes neurofilaments in frozen sections in tissue culture and in formalin fixed sections.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 200
Validation: N/A
Isoform: N/A
Purification: Total IgG fraction
Clonality: Monoclonal
Clone: NAP4
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: N/A
Concentration: N/A
Storage Condition: Neurofilament NF-H antibody can be stored at -20˚C and is stable at -20˚C for at least 1 year.
Alternate Name: N/A
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-H is the neurofilament high or heavy molecular weight polypeptide and runs on SDS-PAGE gels at 200-220 kDa, with some variability across species boundaries. Antibodies to NF-H are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-H antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease.
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