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Product Description
Recombinant ACE2 Antibody, monoclonal | 11-028 | ProSci
Host: Mouse
Reactivity: N/A
Homology: N/A
Immunogen: Recombinant Human ACE2 protein
Research Area: Infectious Disease, COVID-19
Tested Application: WB, IHC
Application: WB:1:1000~4000
IHC:IHC:1:50~100
Specificiy: Human
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein G purified from mice ascites
Clonality: Recombinant Monoclonal
Clone: 180-D-2
Isotype: IgG1
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
Concentration: N/A
Storage Condition: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚C for 1-2 weeks. Store at -20 ˚C for 12 months. Store at -80 ˚C for long term storage.
Alternate Name: Angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, ACEH, ACE-related carboxypeptidase, Metalloprotease MPROT15
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis . Converts angiotensin I to angiotensin 1-9, a nine-amino acid peptide with anti-hypertrophic effects in cardiomyocytes, and angiotensin II to angiotensin 1-7, which then acts as a beneficial vasodilator and anti-proliferation agent, counterbalancing the actions of the vasoconstrictor angiotensin II.
