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Product Description
Flagellin TLR5 Mutant Recombinant Protein | 90-307 | ProSci
Tested Application: N/A
Application: This recombinant proteins is for research use only.
Tpredicted Molecular Weight: N/A
Physical State: Lyophilized
Buffer: Contains PBS. Reconstitute with 100 μl sterile water.
Storage Condition: Stable for at least 6 months after receipt when stored at -20˚C.
Alternate Name: FliC (TLR5 Mutant)
Background: N/A
Shipping: N/A
Disclaimer: Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Source: E. coli
Species: Human, Mouse
By Source: E. Coli
By Species: Human, Mouse
Fusion Tag: His Tag
Sequence: The native flagellin [FliC] from Salmonella enterica Serovar Typhimurium strain ATCC14028 (aa 1-495) contains a substitution of amino acids 90-97 required for TLR5 signaling by a motif from a non-signaling flagellin and is fused at the N-terminus to a His-tag.
Bological Activity: Does not activate TLR5 in human epithelial cell assays based on NF-kappaB luciferase fusions, in vivo on expression of CCL20 or IL-6. It can be used as negative control for TLR5 signaling assays.
Purity: >95% (SDS-PAGE).
Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
