Product Description
SCNN1B Antibody | 18-027 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Monkey
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 406-640 of human SCNN1B (NP_000327.2) .
Research Area: Cancer, Neuroscience, Signal Transduction
Tested Application: WB
Application: WB: 1:500 - 1:2000
Specificiy: N/A
Positive Control 1: 293T
Positive Control 2: LO2
Positive Control 3: Mouse lung
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 75kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: SCNN1B, BESC1, ENaCb, SCNEB, ENaCbeta
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1) , and Liddle syndrome.