Product Description
SRSF7 Antibody | 19-995 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: A synthetic peptide of human SFRS7
Research Area: Neuroscience, Signal Transduction
Tested Application: WB, IHC
Application: WB: 1:500 - 1:1000
IHC: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: HeLa
Positive Control 2: U-87MG
Positive Control 3: A-549
Positive Control 4: LO2
Positive Control 5: 293T
Positive Control 6: 22Rv1
Molecular Weight: Observed: 37kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, pH7.3.
Concentration: N/A
Storage Condition: Store at 4˚C. Avoid freeze / thaw cycles.
Alternate Name: Serine/arginine-rich splicing factor 7, Splicing factor 9G8, Splicing factor, arginine/serine-rich 7, SRSF7, SFRS7
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene is a member of the serine/arginine (SR) -rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding different isoforms have been found for this gene.