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Product Description
IFI16 (CT) Peptide | 9641P | ProSci
Product Type: Peptides
Research Area: N/A
Host Species: N/A
Species Reactivity: N/A
Homology: N/A
Immunogen: N/A
Tested Application: Bl
Predicted MW: N/A
Purification: N/A
Clonality: N/A
Clone: N/A
Isotype: N/A
Conjugate: N/A
Physical State: Liquid
Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Concentration: 200 ug/mL
Storage: Store ULBP1 peptide at -20˚C, stable for one year.
Additional Names: IFI16 Antibody: Gamma-interferon-inducible protein 16, Ifi-16, Interferon-inducible myeloid differentiation transcriptional activator, IFNGIP1
Background: IFI16 Antibody: IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer. Increased expression of IFI16 predicts adverse prognosis in multiple myeloma. IFI16 isoforms with cytoplasmic and nuclear locations play differential roles in recognizing invaded DNA viruses. IFI16 directly senses viral RNA and enhances RIG-I transcription and activation to restrict influenza virus infection. Nuclear sensor IFI16 inhibits the function of Hepatitis B virus covalently closed circular DNA by integrating innate immune activation and epigenetic suppression.
Shipping Condition: Blue Ice
Source: N/A
Species: Human
Peptide Location: 16 amino acids near the carboxyl terminus of human IFI16.
By Source: N/A
By Species: N/A
Recombinant Protein Sequence: N/A
Badges: N/A
