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Product Description
ATF1 (phospho Ser63) Antibody | 79-965 | ProSci
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: ATF1 (phospho Ser63) antibody was raised against a peptide sequence around phosphorylation site of serine 63 (R-P-S (p) -Y-R) derived from Human ATF1 .
Research Area: Phospho-Specific
Tested Application: WB
Application: Western Blot: 1:500~1:1000
Specificiy: The antibody detects endogenous level of ATF1 only when phosphorylated at serine 63.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 29 kDa
Validation: N/A
Isoform: N/A
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+) , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Condition: Store antibody at -20˚C for up to one year.
Alternate Name: ATF1, Activating transcription factor 1, Cyclic-AMP-dependent transcription factor ATF-1, TCR-ATF1, TREB36 protein
User Note: N/A
BACKGROUND: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') , a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.
