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Product Description
CDC25C (phospho Ser198) Antibody | 79-900 | ProSci
Host: Rabbit
Reactivity: Human
Homology: N/A
Immunogen: CDC25C (phospho Ser198) antibody was raised against a peptide sequence around phosphorylation site of Serine 198 (E-F-S (p) -L-K) derived from Human CDC25C.
Research Area: Phospho-Specific
Tested Application: IHC
Application: N/A
Specificiy: The antibody detects endogenous levels of CDC25C only when phosphorylated at serine 198.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 53 kDa
Validation: N/A
Isoform: N/A
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+) , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Condition: Store antibody at -20˚C for up to one year.
Alternate Name: CDC25M1, MPI1B, MPIP3, EC 3.1.3.48
User Note: N/A
BACKGROUND: cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
