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Product Description
Cyclin C (phospho Ser275) Antibody | 79-907 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Cyclin C (phospho Ser275) antibody was raised against a peptide sequence around phosphorylation site of Serine 275 (N-G-S (p) -A-N) derived from Human Cyclin C.
Research Area: Phospho-Specific
Tested Application: WB, IHC
Application: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificiy: The antibody detects endogenous levels of Cyclin C only when phosphorylated at serine 275.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 37 kDa
Validation: N/A
Isoform: N/A
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+) , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Condition: Store antibody at -20˚C for up to one year.
Alternate Name: CG1C, cyclin C, SRB11
User Note: N/A
BACKGROUND: The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene.
