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Product Description
EPB41 (phospho Tyr660/418) Antibody | 79-909 | ProSci
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: EPB41 (phospho Tyr660/418) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 660/418 (N-I-Y (p) -I-R) derived from Human EPB41.
Research Area: Phospho-Specific
Tested Application: WB
Application: Western Blot: 1:500~1:1000
Specificiy: The antibody detects endogenous levels of EPB41 only when phosphorylated at tyrosine 660/418.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 60 kDa
Validation: N/A
Isoform: N/A
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+) , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Condition: Store antibody at -20˚C for up to one year.
Alternate Name: E41P, EPB4.1, band 4.1, P4.1
User Note: N/A
BACKGROUND: Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4.1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.
