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Product Description
MYT1 (phospho Ser83) Antibody | 79-858 | ProSci
Host: Rabbit
Reactivity: Human
Homology: N/A
Immunogen: MYT1 (phospho Ser83) antibody was raised against a peptide sequence around phosphorylation site of Serine 83 (R-V-S (p) -F-R) derived from Human MYT1.
Research Area: Phospho-Specific
Tested Application: IHC
Application: N/A
Specificiy: The antibody detects endogenous levels of MYT1 only when phosphorylated at serine 83.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 54 kDa
Validation: N/A
Isoform: N/A
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+) , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Condition: Store antibody at -20˚C for up to one year.
Alternate Name: PMYT1, PKMYT1, MYT1 kinase
User Note: N/A
BACKGROUND: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2) , and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
