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Product Description
ADAM19 Antibody | 13-541 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 203-460 of human ADAM19 (NP_150377.1) .
Research Area: Cancer, Cell Cycle, Signal Transduction
Tested Application: WB, IF
Application: WB: 1:1000 - 1:2000
IF: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: HT-1080
Positive Control 2: SW480
Positive Control 3: NIH/3T3
Positive Control 4: Mouse heart
Positive Control 5: Mouse lung
Positive Control 6: Mouse liver
Molecular Weight: Observed: 72kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: ADAM19, ADAM metallopeptidase domain 19, MADDAM, MLTNB, ADAM 19, a disintegrin and metalloproteinase domain 19 (meltrin beta) , disintegrin and metalloproteinase domain-containing protein 19, meltrin beta, meltrin-beta, metalloprotease and disintegrin dend
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease.
