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Product Description
beta 2 Microglobulin Antibody, KO Validated | 14-403 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat, Monkey
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-119 of human beta 2 Microglobulin (NP_004039.1) .
Research Area: Cancer
Tested Application: WB, IHC, IP
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IP: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: Jurkat
Positive Control 2: COS7
Positive Control 3: HeLa
Positive Control 4: K-562
Positive Control 5: Mouse liver
Positive Control 6: Mouse spleen
Molecular Weight: Observed: 12kDa
Validation: Antibody is Knockout validated.
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: B2M Antibody: Beta-2-microglobulin
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
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