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Product Description
CHRNE Antibody | 13-399 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-239 of human CHRNE (NP_000071.1) .
Research Area: Neuroscience
Tested Application: WB
Application: WB: 1:1000 - 1:4000
Specificiy: N/A
Positive Control 1: HepG2
Positive Control 2: Mouse skeletal muscle
Positive Control 3: Rat kidney
Positive Control 4: Rat skeletal muscle
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 45kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: CHRNE, ACHRE, CMS1D, CMS1E, CMS2A, FCCMS, SCCMS
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.
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