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Product Description
CRKL Antibody, KO Validated | 14-122 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-303 of human CRKL (NP_005198.1) .
Research Area: Cancer, Immunology, Neuroscience, Signal Transduction
Tested Application: WB, IF
Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: LO2
Positive Control 2: Jurkat
Positive Control 3: SKOV3
Positive Control 4: Mouse brain
Positive Control 5: Rat heart
Positive Control 6: N/A
Molecular Weight: Observed: 37kDa
Validation: Antibody is Knockout validated.
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: CRKL, v-crk sarcoma virus CT10 oncogene homolog (avian) -like, v-crk avian sarcoma virus CT10 oncogene homolog-like,
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
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![[KO Validated] CRKL Rabbit pAb](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/396023/574496/unnamed-776x1024__91681.1646254488__92229.1646256048__34172.1646652109.png?c=2 "[KO Validated] CRKL Rabbit pAb")
